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CK-666 ≥98% (HPLC), powder | Sigma-Aldrich CK-666 is a cell-permeable inhibitor of actin assembly mediated by actin-related protein Arp2/3 complex. CK-666 binds to Arp2/3 complex, stabilizes the inactive state of the complex and prevents its movement into active conformation. CK-666 may be used to study Arp2/3-mediated 麻辣双娇下载

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Arp2/3 complex–dependent actin networks constrain myosin II Jun 18, 2012 - Growth cones were treated with vehicle (DMSO, top panel), CK666 (100 µM, second panel), the inactive analogue CK689 (100 µM, third panel)